Clubfoot relapse: does presentation differ based on age at initial relapse?

Clubfoot relapse: does presentation differ based on age at initial relapse?

PURPOSE Treatment of idiopathic clubfoot with the Ponseti method is now standard, but predicting relapse can be difficult. Most experts recommend bracing to the age of four years, but this can be challenging for families, and may not be necessary in all patients. The purpose of this study is to compare patterns of bracing and age of relapse to help determine if predictable patterns exist. MET...

Testing for discordance at metastatic relapse: does it matter?

In the articles that accompany this editorial, two studies are reported that challenge the belief that a biopsy at the time of metastatic breast cancer relapse is not routinely required, because it provides no further information in regard to the optimal treatment of an individual patient’s tumor. Amir et al report on a prospective trial assessing the clinical impact of tissue confirmation of m...

Relapse of duodenal ulcer: does it matter which drug is used in initial treatment?

Does treatment with cimetidine extended beyond initial healing of duodenal ulcer reduce the subsequent relapse rate?

Cimetidine 1 g daily is often continued for a fixed period beyond the time of healing of duodenal ulcer on the assumption that it might reduce the subsequent relapse rate. To test this, 194 patients whose ulcers had healed after one month of cimetidine 1 g daily were allocated at random to three groups for further treatment with cimetidine 1 g daily for two months (n = 63) or five months (n = 6...

effectiveness of mindfulness-based relapse prevention on relapse rate in opioid dependents: a randomize control trial

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